Genetic Diagnostics
CancerNeo®
Personalized cancer treatment is advancing quickly, with personalized cancer vaccines emerging as a promising approach.
Cells display peptides that reflect their internal state. Immune cells detect abnormal peptides—neoantigens—caused by tumor mutations and use them as targets for destroying cancer cells.
CeGaT’s CancerNeo® analyzes the tumor exome to identify somatic mutations, determine HLA types, and predict neoantigens. Their expression is confirmed through RNA sequencing of the same sample. This enables the design of personalized vaccines to enhance the immune response against cancer.
CancerAdvice®
Molecular tumor analyses have contributed significantly to a better understanding of tumor diseases. However, as they are often very complex and medical progress with drug approvals is developing rapidly, searching for therapies is very time-consuming. CancerAdvice® provides detailed information on targeted therapy recommendations for your patients, including in-label use, off-label use, and information on clinical trials.
CancerPrecision®
CancerPrecision® delivers comprehensive genomic profiling to support personalized cancer therapy. Using NGS, over 700 tumor-associated genes and fusions in 30+ genes are analyzed to detect mutations driving tumor growth and resistance.
Optional RNA analysis identifies novel and known fusion transcripts in 200+ genes. The panel also includes TMB, MSI, HRD, and viral markers (HPV, EBV, MCV, CMV), offering key insights for targeted and immunotherapy.
Results are provided in 2–3 weeks in a detailed report to guide the best treatment decisions.
CancerFusionRx®
Gene fusions are often drivers of cancer. Therefore, drugs targeting these gene fusions are increasingly used in treating tumor patients.
CancerFusionRx® is a unique method to detect structural changes (gene fusions) at the RNA level. This method is far superior to DNA-based methods and transcriptome-level approaches and allows the detection of all known as well as novel gene fusions. Based on the gene fusions found, we can provide specific drug recommendations. CancerFusionRx® is thus a valuable tool in genetic tumor diagnostics and supports you in choosing
the best possible therapy.